You can remove busses that you no longer need.
Procedure
In the Audio Connections window, do one of the following:
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To remove a single bus, right-click the bus in the list and select Remove Bus.
Alternatively, you can select the bus and press Backspace.
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To remove multiple input or output busses at the same time, use Shift or Ctrl/Cmd to select them in the list, right-click them, and select Remove Selected Busses.